Chlamydia pneumoniaeInduces Interleukin‐10 Production that Down‐Regulates Major Histocompatibility Complex Class I Expression

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Chlamydia pneumoniae induces interleukin-10 production that down-regulates major histocompatibility complex class I expression.

Recently, it was demonstrated that CD8(+) T cells are important for the response against Chlamydia pneumoniae. By use of the human monocytic cell line U937 and human monocytes taken from peripheral blood, we investigated the effect of infection on various molecules critical for CD8(+) T cell function. A strong secretion of interleukin (IL)-10 by infected cells was observed, together with an inh...

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Major Histocompatibility Complex, Class I, B

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ژورنال

عنوان ژورنال: The Journal of Infectious Diseases

سال: 2000

ISSN: 0022-1899,1537-6613

DOI: 10.1086/315856